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FLASH GENE
Symbol TRIM58 contributors: KTN/npt - updated : 09-02-2009
HGNC name tripartite motif-containing 58
HGNC id 24150
Location 1q44      Physical location : 248.020.500 - 248.043.436
Synonym name protein BIA2
Synonym symbol(s) BIA2, DKFZp434C091
DNA
TYPE functioning gene
STRUCTURE 22.94 kb     6 Exon(s)
MAPPING cloned Y linked N status confirmed
Map cen - D1S423 - D1S2836 - TRIM58 - D1S2682 - qter
Authors UCSC (2009)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 5158 54.6 486 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervousperipherous   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a RING-type zinc finger
  • B box-type zinc finger
  • a coiled-coil domain
  • a B30.2/SPRY domain
    • HOMOLOGY
    interspecies homolog to murine Trim58 (79.9 pc)
    homolog to rattus Trim58 (80.1 pc)
    Homologene
    FAMILY
  • TRIM/RBCC family
  • C-IV TRIM family
    • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    basic FUNCTION
  • acting as an ubiquitin-protein ligase
    • CELLULAR PROCESS protein, ubiquitin dependent proteolysis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS