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FLASH GENE
Symbol TRIM49 contributors: KTN/npt - updated : 10-02-2009
HGNC name tripartite motif-containing 49
HGNC id 13431
Location 11q14.3      Physical location : 89.530.823 - 89.541.743
Synonym name
  • testis specific RING finger protein
  • ring finger protein 18
    • Synonym symbol(s) RNF18
    DNA
    TYPE functioning gene
    STRUCTURE 10.92 kb     8 Exon(s)
    MAPPING cloned Y linked N status confirmed
    Map cen - D11S4082 - D11S1780 - TRIM49 - D11S4175 - D11S931 - qter
    Authors UCSC (2009)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 2163 52.8 452 - Yoshikawa (2000)
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    Reproductivemale systemtestis   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a RING-zinc type finger motif
  • a B box
  • a coiled-coil domain
  • a B30.2/SPRY domain
    • conjugated MetalloP
    HOMOLOGY
    intraspecies homolog to SSA-RO52
    Homologene
    FAMILY
  • apolipoprotein A1/A4/E family
  • C-IV TRIM family
  • C3HC4 subfamily
    • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION unknown
    CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS