Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TRHR | contributors: mct/npt - updated : 25-03-2009 |
HGNC name | thyrotropin-releasing hormone receptor |
HGNC id | 12299 |
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Corresponding disease |
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Location | 8q23.1 Physical location : 110.099.675 - 110.131.810 | ||
Synonym name | thyroliberin receptor | ||
Synonym symbol(s) | MGC141920, TRH-R |
DNA |
TYPE | functioning gene |
STRUCTURE | 32.09 kb 2 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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|
EXPRESSION |
Type |
constitutive of |
expressed in | (based on citations) |
organ(s) |
tissue |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
conjugated | GlycoP |
HOMOLOGY |
interspecies | ortholog to rattus Trhr |
ortholog to murine Trhr |
Homologene |
FAMILY |
CATEGORY | signaling hormone , receptor |
SUBCELLULAR LOCALIZATION | plasma membrane |
text | integral membrane protein |
basic FUNCTION | |
| |
|
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | hormonal , signal transduction |
thyroid |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | TRHRD |
Susceptibility | to low lean body mass (LBM) |
Variant & Polymorphism SNP | two SNPs, rs16892496 and rs7832552 , within the thyrotropin-releasing hormone receptor (TRHR) gene were significantly associated with LBM (Liu 2009) |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |