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FLASH GENE
Symbol TRGV3 contributors: - updated : 26-01-2004
HGNC name T cell receptor gamma variable 3
HGNC id 12288
Location 7p14      Physical location : -
Synonym name T cell receptor gamma variable 3, subgroup 1
Synonym symbol(s) TCRGV3, V1S3
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 0.00 kb     1 Exon(s)
MAPPING cloned Y linked N status confirmed
Map see TRG@
Physical map
TRGC2 7p14 T cell receptor gamma constant 2 TRGJ2 7p14 T cell receptor gamma joining 2 TRGJP2 7p14 T cell receptor gamma joining P2 TRGC1 7p14 T cell receptor gamma constant 1 LOC392890 7 similar to keratin 8, type II cytoskeletal - human TRGJ1 7p14 T cell receptor gamma joining 1 TRGJP 7p14 T cell receptor gamma joining P TRGJP1 7p14 T cell receptor gamma joining P1 TRGV11 7p14 T cell receptor gamma  variable 11 TRGVB 7p14 T cell receptor gamma variable B TRGV10 7p14 T cell receptor gamma  variable 10 MGC14289 7q34 similar to RIKEN cDNA 1200014N16 gene LOC392661 7 hypothetical gene supported by AK124132; BC045803 TRGV9 7p14 T cell receptor gamma variable 9 TRGVA 7p14 T cell receptor gamma variable A ZC3HAV1 7q34 zinc finger CCCH type, antiviral 1 TRGV8 7p14 T cell receptor gamma variable 8 TRGV7 7p14 T cell receptor gamma variable 7 TRGV6 7p14 T cell receptor gamma variable 6 TRGV5P 7p14 T cell receptor gamma variable 5P TRGV5 7p14 T cell receptor gamma variable 5 TRGV4 7p14 T cell receptor gamma variable 4 VPS41 7p14.1-p13 vacuolar protein sorting 41 (yeast) TRGV3 7p14 T cell receptor gamma variable 3 TRGV2 7p14 T cell receptor gamma variable 2 TRGV1 7p14 T cell receptor gamma  variable 1 AMPH 7p14-p13 amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen) FLJ12571 7q34 hypothetical protein FLJ12571
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticthymus    
Lymphoid/Immunelymph node    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/ImmuneT cell
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo, fetal
Text thymocyte
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a variable gamma domain, folded into a Ig-like domain with both ends joined by a disulfide bond
  • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY immunoglobulin superfamily
    CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION antigen binding
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    text cellular immunity
    PATHWAY
    metabolism
    signaling
    a component component of the T cell receptor, type 1, which is a disulfide bound heterodimer of a gamma and delta chains
    INTERACTION
    DNA
    RNA
    small molecule other,
    binding fragmented antigens, mainly bacterial, in a MHC restricted way
    protein
  • forming wih a TRDV protein, the binding site where the antigen is presented by a MHC molecule
  • cell & other antigen presenting cells
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS