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FLASH GENE
Symbol TREH contributors: np/ - updated : 05-12-2006
HGNC name trehalase (brush-border membrane glycoprotein)
HGNC id 12266
Location 11q23.3      Physical location : 118.528.941 - 118.550.381
Synonym name
  • alpha,alpha-trehalase
  • alpha,alpha-trehalose glucohydrolase
    • Synonym symbol(s) TRE2, TREA, MGC129621
    EC.number 3.2.1.28
    DNA
    TYPE functioning gene
    STRUCTURE 21.44 kb     15 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    15 - 1874 - 583 - 1997 9427547
    EXPRESSION
    Rna function mainly in the kidney, liver and small intestine
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a typical cleavable signal peptide at amino terminus
  • five potential glycosylation sites
  • a hydrophobic region at carboxyl terminus
    • conjugated GlycoP
    mono polymer homomer , dimer
    HOMOLOGY
    interspecies homolog to murine Treh
    Homologene
    FAMILY
  • glycosyl hydrolase 37 family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • probably involved in the hydrolysis of ingested trehalose
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS