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FLASH GENE
Symbol TRBV18 contributors: - updated : 25-01-2004
HGNC name T cell receptor beta variable 18
HGNC id 12193
Location 7q34      Physical location : -
Synonym symbol(s) TCRBV18S1, TRBV18
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 0.00 kb     1 Exon(s)
MAPPING cloned Y linked N status confirmed
Map see TRB@
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticthymus    
Lymphoid/Immunelymph node    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/ImmuneT cell
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo, fetal
Text thymocyte
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a variable beta domain, folded into a Ig-like domain, with both ends joined by a disufide bond
  • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION antigen binding
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    text cellular immunity
    PATHWAY
    metabolism
    signaling
    a component component of the T cell receptor, type 2, which is a disulfide bound heterodimer of an alpha and a beta chain
    INTERACTION
    DNA
    RNA
    small molecule other,
    binding the fragmented antigens in a MHC restricted way
    protein forming the antigen binding site with a TRAV protein
    cell & other antigen presenting cell
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS