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FLASH GENE
Symbol TRBD2 contributors: - updated : 25-01-2004
HGNC name T cell receptor beta diversity 2
HGNC id 12159
Location 7q34      Physical location : -
Synonym symbol(s) TCRBD2
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text
  • component if the distal cluster of TRBD/J/C genes
  • a recombination sequence (RSS) at both ends
    • MAPPING cloned Y linked N status confirmed
    Map see TRB@ and TRBJ@
    Authors Lefranc (IMGT) 03
    Physical map
    TRBVB 7q34 T cell receptor beta variable B TRBV27 7q34 T cell receptor beta variable 27 TRBV28 7q34 T cell receptor beta variable 28 TRBV29-1 7q34 T cell receptor beta variable 29-1 PRSS1 7q35 protease, serine, 1 (trypsin 1) TRY5 7q34 trypsinogen B TRY6 7q34 trypsinogen C TRY7 7q34 trypsinogen D PRSS2 7q35 protease, serine, 2 (trypsin 2) TRBD1 7q34 T cell receptor beta diversity 1 TRBJ1-1 7q34 T cell receptor beta joining 1-1 TRBJ1-2 7q34 T cell receptor beta joining 1-2 TRBJ1-3 7q34 T cell receptor beta joining 1-3 TRBJ1-4 7q34 T cell receptor beta joining 1-4 TRBJ1-5 7q34 T cell receptor beta joining 1-5 TRBJ1-6 7q34 T cell receptor beta joining 1-6 TRBC1 7q34 T cell receptor beta constant 1
    regionally located distal to TRBV@ and the first cluster ot TRBD/J/C genes, proximal to TRBV30
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticthymus    
    Lymphoid/Immunelymph node    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Lymphoid    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Lymphoid/ImmuneT cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period embryo, fetal
    Text thymocyte
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains inserted in the beta chain, between the V and the J segments
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION linking a V to a J segment
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    text cellular immunity
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS