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FLASH GENE
Symbol TRBC2 contributors: - updated : 27-01-2004
HGNC name T cell receptor beta constant 2
HGNC id 12157
Location 7q34      Physical location : -
Synonym symbol(s) TCRBC2
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 0.00 kb     4 Exon(s)
MAPPING cloned Y linked Y status confirmed
Map see TRB@ and TRBJ@
Physical map
TRY5 7q34 trypsinogen B TRY6 7q34 trypsinogen C TRY7 7q34 trypsinogen D PRSS2 7q35 protease, serine, 2 (trypsin 2) TRBD1 7q34 T cell receptor beta diversity 1 TRBJ1-1 7q34 T cell receptor beta joining 1-1 TRBJ1-2 7q34 T cell receptor beta joining 1-2 TRBJ1-3 7q34 T cell receptor beta joining 1-3 TRBJ1-4 7q34 T cell receptor beta joining 1-4 TRBJ1-5 7q34 T cell receptor beta joining 1-5 TRBJ1-6 7q34 T cell receptor beta joining 1-6 TRBC1 7q34 T cell receptor beta constant 1 TRBD2 7q34 T cell receptor beta diversity 2 TRBJ2-1 7q34 T cell receptor beta joining 2-1 TRBJ2-2 7q34 T cell receptor beta joining 2-2 TRBJ2-2P 7q34 T cell receptor beta joining 2-2P TRBJ2-3 7q34 T cell receptor beta joining 2-3 TRBJ2-4 7q34 T cell receptor beta joining 2-4 TRBJ2-5 7q34 T cell receptor beta joining 2-5 TRBJ2-6 7q34 T cell receptor beta joining 2-6 TRBJ2-7 7q34 T cell receptor beta joining 2-7
regionally located located upstream of TRBV30, at the distal end of the TRB@ cluster
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticthymus    
Lymphoid/Immunelymph node    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/ImmuneT cell
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo, fetal
Text thymocyte
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N-terminal extracellular segment, folded into one constant Ig-like domain
  • a transmembrane segment (TM1)
  • a shirt cytoplasmic tail
    • HOMOLOGY
    Homologene
    FAMILY immunoglobulin superfamily
    CATEGORY immunity/defense , receptor
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION anchoring the T cell receptor to the plasma membrane
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein binding the cognate constant alpha chain by a disulfide bond
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS