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FLASH GENE
Symbol TRAV29DV5 contributors: - updated : 25-01-2004
HGNC name T cell receptor alpha variable 29/delta variable 5, rearranged to either TRDD or TRAJ
HGNC id 12127
Location 14q11.2      Physical location : -
Synonym symbol(s) hADV29S1,TRAV29/DV5,TCRAV21S1
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 0.00 kb     1 Exon(s)
MAPPING cloned Y linked N status confirmed
Physical map
TRAV15 14q11.2 T cell receptor alpha variable 15 TRAV12-3 14q11.2 T cell receptor alpha variable 12-3 TRAV8-6 14q11.2 T cell receptor alpha variable 8-6 TRAV16 14q11.2 T cell receptor alpha variable 16 TRAV17 14q11.2 T cell receptor alpha variable 8-7 TRAV18 14q11.2 T cell receptor alpha variable 18 TRAV19 14q11.2 T cell receptor alpha variable 19 TRAV20 14q11.2 T cell receptor alpha variable 20 TRAV21 14q11.2 T cell receptor alpha variable 21 TRAV22 14q11.2 T cell receptor alpha variable 22 TRAV23DV6 14q11.2 T cell receptor alpha variable 23/delta variable 6, rearranged to either TRDD or TRAJ TRDV1 14q11.2 T cell receptor delta variable 1 TRAV24 14q11.2 T cell receptor alpha variable 24 TRAV25 14q11.2 T cell receptor alpha variable 25 TRAV26-1 14q11.2 T cell receptor alpha variable 26-1 TRAV8-7 14q11.2 T cell receptor alpha variable 8-7 TRAV27 14q11.2 T cell receptor alpha variable 27 TRAV28 14q11.2 T cell receptor alpha variable 28 TRAV29DV5 14q11.2 T cell receptor alpha variable 29/delta variable 5, rearranged to either TRDD or TRAJ TRAV30 14q11.2 T cell receptor alpha variable 30 TRAV31 14q11.2 T cell receptor alpha variable 31 TRAV32 14q11.2 T cell receptor alpha variable 32 TRAV33 14q11.2 T cell receptor alpha variable 33 TRAV26-2 14q11.2 T cell receptor alpha variable 26-2 TRAV34 14q11.2 T cell receptor alpha variable 34 TRAV35 14q11.2 T cell receptor alpha variable 35 TRAV36DV7 14q11.2 T cell receptor alpha variable 36/delta variable 7, rearranged to either TRDD or TRAJ TRAV37 14q11.2 T cell receptor alpha variable 37 TRAV38-1 14q11.2 T cell receptor alpha variable 38-1 TRAV38-2DV8 14q11.2 T cell receptor alpha variable 38-2/delta variable 8, rearranged to either TRDD or TRAJ TRAV39 14q11.2 T cell receptor alpha variable 39 TRAV40 14q11.2 T cell receptor alpha variable 40 TRAV41 14q11.2 T cell receptor alpha variable 41
regionally located one of the TRAV/DV genes interspersed in the TRAV@cluster
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticthymus    
Lymphoid/Immunelymph node    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/ImmuneT cell
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo, fetal
Text thymocyte
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a variable alpha domain of about 110 AAs, folded into a Ig-like domain with both ends joined by a disulfide bond
  • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY immunoglobulin superfamily
    CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION antigen binding
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    text cellular immunity
    PATHWAY
    metabolism
    signaling
    a component component of
  • either the T cell receptor, type 2
  • or the T cell receptor, type 1
  • which are disulfide bound heterodimers alpha/beta or gamma/delta chains, respectively
    INTERACTION
    DNA
    RNA
    small molecule other,
    binding fragmented antigens in a MHC restricted way
    protein
  • forming either wih a TRBV or a TRGV protein, the binding site where the antigen is presented by a MHC molecule
  • cell & other antigen presenting cells
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS