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FLASH GENE
Symbol TRAV24 contributors: - updated : 25-01-2004
HGNC name T cell receptor alpha variable 24
HGNC id 12121
Location 14q11.2      Physical location : -
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 0.00 kb     1 Exon(s)
MAPPING cloned Y linked N status confirmed
Physical map
TRAV8-2 14q11.2 T cell receptor alpha variable 8-2 TRAV8-3 14q11.2 T cell receptor alpha variable 8-3 TRAV13-1 14q11.2 T cell receptor alpha variable 13-1 TRAV12-2 14q11.2 T cell receptor alpha variable 12-2 TRAV8-4 14q11.2 T cell receptor alpha variable 8-4 TRAV8-5 14q11.2 T cell receptor alpha variable 8-5 TRAV13-2 14q11.2 T cell receptor alpha variable 13-2 TRAV14DV4 14q11.2 T cell receptor alpha variable 14/delta variable 4, rearranged to either TRDD or TRAJ TRAV9-2 14q11.2 T cell receptor alpha variable 9-2 TRAV15 14q11.2 T cell receptor alpha variable 15 TRAV12-3 14q11.2 T cell receptor alpha variable 12-3 TRAV8-6 14q11.2 T cell receptor alpha variable 8-6 TRAV16 14q11.2 T cell receptor alpha variable 16 TRAV17 14q11.2 T cell receptor alpha variable 8-7 TRAV18 14q11.2 T cell receptor alpha variable 18 TRAV19 14q11.2 T cell receptor alpha variable 19 TRAV20 14q11.2 T cell receptor alpha variable 20 TRAV21 14q11.2 T cell receptor alpha variable 21 TRAV22 14q11.2 T cell receptor alpha variable 22 TRAV23DV6 14q11.2 T cell receptor alpha variable 23/delta variable 6, rearranged to either TRDD or TRAJ TRDV1 14q11.2 T cell receptor delta variable 1 TRAV24 14q11.2 T cell receptor alpha variable 24 TRAV25 14q11.2 T cell receptor alpha variable 25 TRAV26-1 14q11.2 T cell receptor alpha variable 26-1 TRAV8-7 14q11.2 T cell receptor alpha variable 8-7 TRAV27 14q11.2 T cell receptor alpha variable 27 TRAV28 14q11.2 T cell receptor alpha variable 28 TRAV29DV5 14q11.2 T cell receptor alpha variable 29/delta variable 5, rearranged to either TRDD or TRAJ TRAV30 14q11.2 T cell receptor alpha variable 30 TRAV31 14q11.2 T cell receptor alpha variable 31 TRAV32 14q11.2 T cell receptor alpha variable 32 TRAV33 14q11.2 T cell receptor alpha variable 33 TRAV26-2 14q11.2 T cell receptor alpha variable 26-2 TRAV34 14q11.2 T cell receptor alpha variable 34 TRAV35 14q11.2 T cell receptor alpha variable 35 TRAV36DV7 14q11.2 T cell receptor alpha variable 36/delta variable 7, rearranged to either TRDD or TRAJ
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticthymus    
Lymphoid/Immunelymph node    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/ImmuneT cell
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo, fetal
Text thymocyte
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a variable alpha domain of about 110 AAs, folded into a Ig-like domain with both ends joined by a disulfide bond
    • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY immunoglobulin superfamily
    CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION antigen binding
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    text cellular immunity
    PATHWAY
    metabolism
    signaling
    a component component of the T cell receptor, type 2, which is a disulfide bound heterodimer of an alpha and a beta chain
    INTERACTION
    DNA
    RNA
    small molecule other,
    binding fragmented antigens in a MHC restricted way
    protein
  • forming wih a TRBV protein, the binding site where the antigen is presented by a MHC molecule
    • cell & other antigen presenting cells
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS