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FLASH GENE
Symbol TRAPPC6B contributors: KTN/npt - updated : 23-01-2009
HGNC name trafficking protein particle complex 6B
HGNC id 23066
Location 14q21.1      Physical location : 39.617.014 - 39.639.634
Synonym symbol(s) TPC6, FLJ17772, FLJ79549
DNA
TYPE functioning gene
STRUCTURE 22.62 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Map cen - D14S286 - D14S1048 - TRAPPC6B - D14S278 - D14S1039 - qter
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 3364 17.9 158 - -
5 splicing 3280 14.6 130 - -
  • lacking an alternate in-frame exon in the mid-coding region compared to variant 1
  • EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinesmall intestine   
     mouthtongue   
    Nervousbrain    
    Reproductivefemale systemuterus   
    Urinarybladder    
     kidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period embryo
    Text stem cells
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer homomer , heteromer , dimer
    HOMOLOGY
    interspecies homolog to rattus Trappc6b (98.7 pc)
    homolog to murine Trappc6b (97.5 pc)
    Homologene
    FAMILY
  • TRAPP small subunits family
  • BET3 subfamily
  • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • involved in vesicle-mediated transport
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text ER-Golgi transport
    PATHWAY
    metabolism
    signaling
    a component
  • part of the multisubunit TRAPP (transport protein particle) complex (Kummel 2005)
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with TRAPPC3 in heterodimer (Kummel 2005)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS