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FLASH GENE
Symbol TRAPPC10 contributors: mct/npt - updated : 22-12-2009
HGNC name trafficking protein particle complex 10
HGNC id 11868
Location 21q22.3      Physical location : 45.432.205 - 45.526.430
Synonym name
  • epilepsy, holoprosencephaly, candidate-1 (see APECED, EPM1)
  • transmembrane protein 1
  • trafficking protein particle complex subunit 130
  • transport protein particle subunit TMEM1
  • TRAPP 130 kDa subunit
  • Synonym symbol(s) EHOC1, GT334, EH01, TMEM1, EHOC-1, FLJ54223, FLJ54817, FLJ55683, MGC126777, TRS130, TRS30
    DNA
    TYPE functioning gene
    STRUCTURE 94.23 kb     23 Exon(s)
    MAPPING cloned Y linked N status confirmed
    Map cen - TMEM1 - D21S1460 - PWP2H - C21orf33 - D21S25 - PGA1 - C21orf2 - PFKL PFKL - D21S154 - qter
    Authors Yamakawa (95), Wiltshire (99)
    Text see PWP2H
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    23 - 6970 - 1259 - Lafreniere (1997)
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Reproductivemale systemprostate   
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • ATP binding cassette, multiple putative transmembrane domains
  • HOMOLOGY
    interspecies homolog to murine Tmem1
    intraspecies homolog to transmembrane protein 1 candidate gene
    Homologene
    FAMILY
  • TMEM1 family
  • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • playing a role in vesicular transport from reticulum endoplasmic to golgi
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS facilitated diffusion transport
    text sodium channel
    PATHWAY
    metabolism
    signaling
    a component
  • part of the TRAPPII complex that contains the mammalian homologues of yeast Trs120 and Trs130 (TRAPPC9 and TRAPPC10)
  • INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ATP
  • protein
  • FMR1 (RNA target of FMR1)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS