basic FUNCTION
| inducible molecule taking part in the signal transduction of TNFR2 (TNFRSF1B),LTBR, CD40,(TNFRSF5, CD30 (TNFRSF8, LMP1 |
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involved in the blockage of apoptotic pathway |
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regulates CD40-induced TRAF2-mediated NF-kappaB activation  |
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differentially affects TRAF2 recruitment and activation of NF-kappaB by members of the TNF receptor family  |
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substrate of PKN1 kinase activity, and the phosphorylation event is required for attenuating downstream kinase activities  |
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important molecule mediating both the TNFRSF8 signaling-dependent and independent NF-kappaB activation, which prevents the lymphoma cells from spontaneous and induced apoptosis  |