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FLASH GENE

Symbol

TPRG1

contributors: mct - updated : 28-10-2010

HGNC name	tumor protein p63 regulated 1
HGNC id	24759

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	3q28      Physical location : 188.889.762 - 189.041.270
Synonym name	family with sequence similarity 79, member B
	hypothetical protein LOC285386
Synonym symbol(s)	FAM79B, FLJ41238, FLJ43694, MGC126599, MGC126601

DNA

TYPE	functioning gene
STRUCTURE	376.35 kb     6 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_198485 6 - 3665 NP_940887 31.2 275 - 2008 18256694

EXPRESSION

Type

widely

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive mouth tongue     highly Reproductive female system breast mammary gland   highly   male system prostate     moderately Respiratory respiratory tract larynx     highly Skin/Tegument skin       predominantly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial barrier lining epidermis

cells

System Cell Pubmed Species Stage Rna symbol Skin/Tegument keratinocyte

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

TPRG1 family

CATEGORY

unknown/unspecified

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm

basic FUNCTION

unknown

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

physically associated with the TP63 gene during evolution, and directly regulated by TP63 through a long-distance enhancer located within the TPRG1 locus

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS