Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TPMT | contributors: mct/npt - updated : 21-12-2021 |
HGNC name | thiopurine S-methyltransferase |
HGNC id | 12014 |
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Corresponding disease |
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Location | 6p22.3 Physical location : 18.128.545 - 18.155.374 | ||
Synonym name | S-adenosyl-L-methionine:thiopurine S-methyltransferase | ||
Synonym symbol(s) | TPMTD | ||
EC.number | 2.1.1.67 |
DNA |
TYPE | functioning gene |
STRUCTURE | 26.86 kb 9 Exon(s) |
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10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | monomer |
HOMOLOGY |
Homologene |
FAMILY | |
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CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION
| intracellular |
intracellular,cytoplasm,cytosolic |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
inhibited by | s-adenosyl-l-homocysteine (SAH) |
ASSOCIATED DISORDERS |
corresponding disease(s) | MCPS |
Susceptibility |
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Variant & Polymorphism SNP | |
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |