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FLASH GENE
Symbol TOR2A contributors: - updated : 21-06-2005
HGNC name torsin family 2, member A
HGNC id 11996
Location 9q34.11      Physical location : 130.493.803 - 130.497.604
Synonym symbol(s) TORP1, FLJ14771
DNA
TYPE functioning gene
STRUCTURE 3.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
ANGPTL2 9q34 angiopoietin-like 2 DKFZp761J1523 9q34.13 hypothetical protein DKFZp761J1523 SLC2A8 9q34.1-q34.2 solute carrier family 2, (facilitated glucose transporter) member 8 ZNF79 9q34.1 zinc finger protein 79 (pT7) RPL12 9q34 ribosomal protein L12 LRSAM1 9q34.13 leucine rich repeat and sterile alpha motif containing 1 DKFZP434H0820 9q34.13 hypothetical protein DKFZp434H0820 STXBP1 9q34.1 syntaxin binding protein 1 LOC286207 9q34.13 hypothetical protein LOC286207 LOC138428 9q34.13 hypothetical protein LOC138428 TTC16 9q34.13 tetratricopeptide repeat domain 16 TOR2A 9q34.11 torsin family 2, member A SH2D3C 9q34.13 SH2 domain containing 3C CDK9 9q34.1 cyclin-dependent kinase 9 (CDC2-related kinase) FPGS 9cen-q34.11 folylpolyglutamate synthase ENG 9q34.1 endoglin (Osler-Rendu-Weber syndrome 1) AK1 9q34.12 adenylate kinase 1 ST6GALNAC6 9q34.13 adenylate kinase 1 SIAT7D 9q34.1 sialyltransferase 7D ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) MGC46424 9q34.13 hypothetical protein MGC46424 LOC389790 9 similar to phosphatidylinositol phosphate kinase-like protein DPM2 9q34.13 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit FLJ10232 9q34.13 hypothetical protein FLJ10232 DKFZp762G199 9q34.13 hypothetical protein DKFZp762G199 MCSC 9q34.13 mitochondrial Ca2+-dependent solute carrier PTGES2 9q34.13 prostaglandin E synthase 2 LOC389791 9 hypothetical gene supported by AK094537 LCN2 9q34 lipocalin 2 (oncogene 24p3) C9orf16 9q34.1 chromosome 9 open reading frame 16 CIZ1 9q34.13 chromosome 9 open reading frame 16 DNM1 9q34 dynamin 1 GOLGA2 9q34.13 golgi autoantigen, golgin subfamily a, 2
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivesalivary gland   moderately
Lymphoid/Immunespleen   highly
Nervousbrain   moderately
Reproductivefemale systemovary  highly
Respiratorylung   moderately
Urinarybladder   highly
cell lineage
cell lines
fluid/secretion blood
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an ATP-binding domain
  • HOMOLOGY
    interspecies homolog to murine Tor2a
    Homologene
    FAMILY
    CATEGORY chaperone/stress , enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION
  • acting as a GTP cyclohydrolase I
  • acting as a nucleoside-triphosphatase
  • involved in chaperone cofactor dependent protein folding
  • CELLULAR PROCESS protein, post translation, folding
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ATP
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS