Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TNFRSF17 | contributors: mct - updated : 19-01-2016 |
HGNC name | tumor necrosis factor receptor superfamily, member 17 |
HGNC id | 11913 |
|
Location | 16p13.13 Physical location : 12.058.963 - 12.061.924 |
Synonym name | B cells maturation antigen, B cells activation factor |
Synonym symbol(s) | BCM, BCMA, CD269, TNFRSF13A |
DNA |
TYPE | functioning gene |
STRUCTURE | 2.96 kb 3 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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|
EXPRESSION |
Type | restricted |
tissue |
|
cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| |
| |
| |
|
mono polymer | homomer , trimer |
HOMOLOGY |
Homologene |
FAMILY | tumor necrosis factor receptor superfamily |
CATEGORY | receptor membrane |
SUBCELLULAR LOCALIZATION | plasma membrane |
text | type 3 membrane protein |
basic FUNCTION | |
| |
| |
| |
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CELLULAR PROCESS | cell life, differentiation |
PHYSIOLOGICAL PROCESS | development |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
|
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
|
Susceptibility | to UC (ulcerative colitis) and IBD (inflammatory bowel disease) |
Variant & Polymorphism other | |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |
BCMA-/- knockout mice,developing systemic lupus erythematosis |