basic FUNCTION
| involved in angiogenesis and may play a role in cell-matrix interactions |
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may modulate cellular adhesion to matrix |
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proteins |
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required for the expression of myogenic regulatory factors and differentiation of myoblasts into myotubes |
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having a role during myogenic differentiation that could be independent of TWEAK cytokine |
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TWEAK signaling regulates progenitor cell proliferation, differentiation, and survival in multiple organ systems (Hamill 2007) |
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its activation exerts different effects on neural progenitor cells and their progeny depending on the developmental stage of the cells (Hamill 2007) |
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TWEAK/TWEAKR may be important in regulating myocardial structural remodeling and function and may play a role in the pathogenesis of dilated cardiomyopathy (Jain 2009) |