| protein
| binds to elongation factor EEF1A1 and interferes in protein synthesis  |
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calcium modulating cyclophilin ligand CAMLG/CAML as a binding partner |
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ER membrane proteins, ERLIN2 and TMUB1, are associated proteins of mammalian AMFR, a membrane-bound ubiquitin ligase that mediates sterol-accelerated ERAD of the cholesterol biosynthetic enzyme HMGCR |
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TMUB1 plays a negative role in IL6-induced hepatocyte proliferation, indicating that the interaction between TMUB1 and CAMLG may mediate the function of TMUB1 in hepatocytes |
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TMUB1 acts as a functional bridge in NPM1-CDKN2A interactions |
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CEBPB is a key transcription factor, which can positively regulate the expression of TMUB1 during liver cell proliferation through a possible association with IL6 |
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TMUB1 interacting with CAMLg and further interfering with the binding of CAMLG to cyclophilin B to decrease cellular [Ca2+]i |
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STAT3 binds to and activates the promoter of TMUB1, suggesting a putative negative feedback loop between TMUB1 and STAT3 signaling |
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promotes the TP53-dependent mitochondrial apoptosis pathway by preserving cytoplasmic TP53 from both degradation and nuclear uptake |
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causes cell cycle arrest in G0/G1 phase, an event associated to stabilization of CDKN2A, an important tumor suppressor protein |
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function of TMUB1 as a novel modulator of TRAF6, regulating inflammatory responses driven by activation of the NFKB1 signaling pathway |
