Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TMEM18 | contributors: mct/npt - updated : 22-05-2015 |
HGNC name | transmembrane protein 18 |
HGNC id | 25257 |
|
Location | 2p25.3 Physical location : 667.974 - 677.439 |
Synonym symbol(s) | DKFZp434C1714 |
DNA |
TYPE | functioning gene |
STRUCTURE | 9.47 kb 5 Exon(s) |
regulatory sequence | Promoter |
text structure |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
---|
|
EXPRESSION |
Type | widely |
tissue |
|
cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
secondary structure | predicted to be mostly alpha-helical with three transmembrane parts |
HOMOLOGY |
Homologene |
FAMILY |
CATEGORY | DNA associated |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm,organelle,membrane | |
intracellular,cytoplasm,organelle,endoplasmic reticulum | |
intracellular,nucleus | |
intracellular,nuclear envelope | |
text |
basic FUNCTION | |
| |
|
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA | binds to DNA in a sequence-specific manner |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
|
Susceptibility |
|
Variant & Polymorphism SNP | |
| |
| |
Candidate gene
Marker
| Therapy target
| overexpression of this protein could be favorably used in neural stem cells -based glioma therapy (Jurvansuu 2008) |
| |
ANIMAL & CELL MODELS |