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FLASH GENE
Symbol TMEM132E contributors: mct - updated : 11-04-2022
HGNC name transmembrane protein 132E
HGNC id 26991
Corresponding disease
DFNB99 deafness, autosomal recessive 99
Location 17q12      Physical location : 32.907.767 - 32.966.336
Synonym symbol(s) DFNB99
DNA
TYPE functioning gene
STRUCTURE 59.74 kb     9 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 5807 - 1074 - 2020 31656313
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • extra-cellular portions contain five conserved domains including three tandem immunoglobulin domains, and a cohesin domain homologue
    • HOMOLOGY
    Homologene
    FAMILY TMEM132 family
    CATEGORY
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • potential cellular adhesion function for TMEM132 family, connecting the extracellular medium with the intracellular actin cytoskeleton
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) DFNB99
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS