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FLASH GENE
Symbol TMBIM4 contributors: - updated : 01-06-2011
HGNC name transmembrane BAX inhibitor motif containing 4
HGNC id 24257
Location 12q14.3      Physical location : 66.530.717 - 66.563.807
Synonym name
  • CGI-119 protein
  • S1R protein
  • Z-protein
  • Synonym symbol(s) CGI-119, ZPRO, S1R, LFG4, GAAP
    DNA
    TYPE functioning gene
    STRUCTURE 33.09 kb     7 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 1831 - 238 - -
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularvessel   highly
    Digestivepancreas exocrine   highly
    Reproductivefemale systemplacenta  moderately
     male systemtestis  highly
    Urinarykidney   highly
    Visualeye   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to murine Tmbim4
    Homologene
    FAMILY
  • BI1 family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • represent regulators of cell death pathways (Zhou 2008)
  • play a role in apoptosis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS