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FLASH GENE
Symbol TM6SF1 contributors: - updated : 04-09-2007
HGNC name transmembrane 6 superfamily member 1
HGNC id 11860
Location 15q25-q26.1      Physical location : 83.776.323 - 83.806.110
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text
  • component of a cluster of paralogous genes on chromosome 15
    • STRUCTURE 29.00 kb     10 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map cen - D15S114 - SIN3A - ARID3B - HMG20A - EEF2L - SH3GL3 - D15S200 - BTBD1 - D15S202 - TM6SF1 - HAPLN3 - ACAN - MEF2A
    Authors Carim-Todd (00)
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularvessel   predominantly
    Digestivemouth   moderately
     stomach   moderately
    Lymphoid/Immunespleen    
    Reproductivemale systemtestis   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow  moderately
    Lymphoid    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Blood/Hematopoieticleukocyte
    cell lineage
    cell lines
    fluid/secretion highly in blood
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • six transmembrane domains
    • HOMOLOGY
    interspecies homolog to chimpanzee TM6SF1 (99.5 pc)
    homolog to rattus Tm6sf1 (94.1 pc)
    homolog to murine Tm6sf1 (94.3 pc)
    homolog to chicken TM6SF1 (80.3 pc)
    intraspecies paralog to TM6SF2
    Homologene
    FAMILY
  • TM6SF family
    • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS