protein
| activating NFkappa B in response to Gram+ bacteria |
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interaction with CD14 through the extracellular Toll-like receptor 2 domain |
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TLR4 requires myeloid differentiation (LY96), and both TLR2 and TLR4 signal need myeloid differentiation factor (MYD88) |
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RGS2 inhibits STAT3-mediated NOX1 transcription, and can itself be repressed by TLR2 |
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MAP2K1 negatively regulates TLR2 signaling in endothelial cell, MAP2K1 promotes TLR2 signaling in monocytes |
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NOD1 cooperates with TLR2 to enhance T cell receptor-mediated activation in CD8 T cells |
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activation of PRKCH and PLD2 signaling pathway is an important mechanism for regulation of TLR2-induced ABCA1 expression |
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not only TLR4 signaling, but also CD180 appears to be an essential accessory for immune responses through TLR2 signaling |
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activation of TLR2 in the skin by commensal microbial products prevents excessive inflammation by blocking downstream TLR3 signaling |
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TICAM2 is required for the TLR2-dependent movement of MYD88 to endosomes following ligand engagement |
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SLC16A4 is required for macrophage activation upon TLR2 and TLR4 stimulations |
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MAPK7 mediates proinflammatory responses in primary human cells in response to stimulation of TLR2 |
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PRG4 binds to TLR2 and TLR4 and this binding mediates a novel anti-inflammatory role for PRG4 |
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activation of human mast cells by CAMP could be modified by TLR2 ligands and the function of human mast cells could be switched from allergic reactions to innate immune response |
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activation of TLR2 stimulates foam cell formation, which is a key early event in the process of atherosclerosis |
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CSF3 downregulates TLR1, TLR2 and TLR4 in a time- and dose-dependent fashion in human monocytes |
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critical role of SPI1 in the regulation of TLR1, 2, 4 and of CD14 |