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FLASH GENE
Symbol TLL2 contributors: npt/ - updated : 16-02-2005
HGNC name tolloid-like 2
HGNC id 11844
Location 10q23-q24      Physical location : 98.124.362 - 98.273.683
Synonym name related to procollagen C proteinase
Synonym symbol(s) KIAA0932, MGC133312, MGC133313
EC.number 3.4.24.-
DNA
TYPE functioning gene
STRUCTURE 149.30 kb     21 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
21 - 6753 113.4 1015 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo, pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a signal peptide
  • a proregion the protease domain
  • five CUB domain
  • an EGF domain
    • conjugated GlycoP
    HOMOLOGY
    intraspecies paralog to TLL1
    homolog to procollagen C proteinase
    paralog to TLL1
    Homologene
    FAMILY
  • astacin family of metalloproteinases
  • peptidase M12A family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • metallopeptidase activity
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Ca2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS