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FLASH GENE
Symbol TLE6 contributors: npt/SGE - updated : 27-07-2010
HGNC name transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
HGNC id 30788
Location 19p13.3      Physical location : 2.977.535 - 2.995.182
Synonym name transducin-like enhancer of split 6
Synonym symbol(s) FLJ14009, GRG6, MGC14966
DNA
TYPE functioning gene
STRUCTURE 17.65 kb     17 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
17 - 2033 - 572 - -
16 - 1955 - 449 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven WD repeats
  • HOMOLOGY
    Homologene
    FAMILY
  • WD repeat Groucho/TLE family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • might play an essential role for zygotes to progress beyond the first embryonic cell divisions (Li 2008)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component member of the subcortical maternal complex (SCMC)
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • maybe directly interacting with OOEP and NLRP5 (li 2008)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS