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FLASH GENE
Symbol TIFAB contributors: npt - updated : 19-11-2005
Location 5q31.1      Physical location : 134.784.559 - 134.788.089
Genatlas name TIFA-related protein TIFAB
Synonym name TRAF-interacting protein with a forkhead-associated domain
Synonym symbol(s) FLJ00292
DNA
TYPE functioning gene
STRUCTURE 22.00 kb     6 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 1285 - 161 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • inhibiting TIFA-mediated activation of NFkappaB
  • inhibiting the TIFA-mediated TRAF6 activation possibly by inducing a conformational change in TIFA
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS