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FLASH GENE
Symbol THYN1 contributors: - updated : 10-03-2007
HGNC name thymocyte nuclear protein 1
HGNC id 29560
Location 11q25      Physical location : 134.118.174 - 134.123.260
Genatlas name thymocyte protein thy28
Synonym symbol(s) MY105, MDS012, HSPC144, THY28, MGC12187 , THY28KD
DNA
TYPE functioning gene
STRUCTURE 5.00 kb     7 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 1323 25 225 blood Jiang, Song
seven exons encoding the longest transcript
- splicing 862 18 166 bladder Jiang, Song
lacking two internal segments (one in the 5'UTR, one in the coding region), encoding a shorter isoform with a distinct C terminus
- splicing 1013 25 225 blood Jiang, Song
  • lacking an internal segment in the 5'UTR
  • eight exons
  • - - 790 - 166 - Song
    - - 941 - 225 - Song
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivepharynx   highly
     salivary gland   highly
    Endocrineparathyroid   highly
     thyroid   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    a DUF589 domain
    HOMOLOGY
    interspecies homolog to murine Thy28
    homolog to rattus MGC72984
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may be involved in apoptosis of lymphocytes
  • might play some role in the positive-negative selection step in thymic maturation
  • CELLULAR PROCESS cell life, cell death/apoptosis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS