Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol THADA contributors: SGE/npt - updated : 13-07-2010
HGNC name thyroid adenoma associated
HGNC id 19217
Location 2p21      Physical location : 43.457.975 - 43.823.185
Synonym name
  • thyroid adenoma associated protein
  • death receptor-interacting protein
  • gene inducing thyroid adenomas protein
  • Synonym symbol(s) GITA, FLJ21877, FLJ44016, FLJ44876, KIAA1767, FLJ77530
    DNA
    TYPE functioning gene
    STRUCTURE 365.21 kb     38 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    38 - 6134 - 1953 - Rippe (2003)
    38 - 6346 - 1953 - Rippe (2003)
    24 exons
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinesmall intestine   
     liver   highly
     stomach    
    Endocrinepancreas    
     thyroid    
    Lymphoid/Immunethymus    
    Reproductivefemale systemuterus   
     male systemtestis   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    conjugated PhosphoP
    HOMOLOGY
    interspecies homolog to rattus Thada (79.8pc)
    homolog to murine Thada (79.0pc)
    Homologene
    FAMILY
  • THADA family
  • CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • a death receptor-interacting protein
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   translocation    
    aberrantly rearranged in thyroid adenomas (Drieschner 2007)
    Susceptibility to Polycystic ovary syndrome (PCOS)
    Variant & Polymorphism SNP associated with Polycystic ovary syndrome (PCOS)
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS