basic FUNCTION
| can stimulate E2F-dependent transcription, and negative regulator of the E2F activity |
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cancer-testis antigen |
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having biological functions that may influence our current perspective of how E2F activities are orchestrated in normal cells and how they are disturbed in such pathological conditions as cancer |
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role for TFDP3 in regulating E2F1 activity during the DNA damage response |
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inactivates transcription, and has the opposite effect compared with TFDP1 on E2F site transcription |
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influences cell cycle progression, under both normal and DNA damage conditions |
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acts as a transcription factor during epithelial-mesenchymal transition |
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functions as a regulator in epithelial-mesenchymal transition |
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contributes toward tumor cell resistance |