protein
| Eps15 (EDH5) for receptor-mediated endocytosis |
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interacts with WWOX and with CITED4 |
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associating with AAK1 (phosphorylates the micro2 subunit of TFAP2A and regulates its recruitment to tyrosine-based internalization motifs found on membrane-bound receptors)  |
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interacting with KCTD1 (significantly repressed TFAP2-mediated transactivation through the BTB domain)  |
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essential role for TFAP2A in MUC8 gene expression  |
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binds CDKN1A to two regions of the promoter: the proximal region where the AP-2 site lies and upstream near the major TP53 binding site  |
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plays a negative role in regulating CHRNA7 transcription  |
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possible interaction between FOXD1 and TFAP2A  |
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in neural crest cells TFAP2A directly activates expression of SOX10, which encodes a transcription factor essential for neural crest development  |
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synergistic effects of HRK promoter hypermethylation and loss of TFAP2A transactivation lead to HRK gene silencing and confer resistance to apoptosis and enhanced tumor growth  |
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CAPN7 interacted with activator protein 2 (TFAP2A), an important transcription factor of MMP2  |
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MYO6 functions in endocytosis in conjunction with binding partners including adaptor protein (TFAP2A, DAB2, and GIPC1)  |
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TFAP2A regulates activated F2R signaling by altering receptor surface expression and through recruitment of regulator of G protein signaling (RGS) proteins  |