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Symbol TENM4 contributors: mct - updated : 24-10-2012
HGNC name teneurin transmembrane protein 4
HGNC id 29945
Location 11q14.1      Physical location : -
Synonym name
  • odz, odd Oz/ten-m homolog 4 (Drosophila)
  • tenascin-M4
  • Synonym symbol(s) Doc4, Ten-M4, ODZ4, TNM4, Doc4
    DNA
    TYPE functioning gene
    STRUCTURE 787.37 kb     34 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    34 - 13566 - 2769 - 2002 12000766
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivemouthtongue  predominantly
     stomach   highly
    Nervousbrain   moderately
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a putative signal peptide
  • eight EGF-like repeats
  • a putative transmembrane domain followed by
  • a 1800-amino-acid stretch without homology to any proteins outside of this family
  • mono polymer homomer , dimer
    HOMOLOGY
    interspecies ortholog to murine Odz4
    ortholog to chicken TEN4
    Homologene
    FAMILY Ten-m/Odz/teneurins family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type II transmembrane molecule
    basic FUNCTION
  • regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component dimerized in a covalent, disulfide-linked fashion
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS