SUBCELLULAR LOCALIZATION
| intracellular
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| intracellular,cytoplasm,cytoskeleton,microtubule,mitotic spindle
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text
| ciliary and flagellar microtubules |
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associates with the spindle poles throughout mitosis, organizes the spindle midzone microtubules during anaphase, and assembles into the midbody matrix surrounding the compacted midzone microtubules during cytokinesis |
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in spermatozoa, might be present in the peri-axonemal component, not directly associated with axonemal tubulins |
basic FUNCTION
| playing a role in the formation of the sperm flagella and/or sperm mobility |
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filament-forming protein coassembled with tubulins to form ciliary and flagellar microtubules |
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may playing a role in spermatogenesis |
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required for central spindle microtubule organization and the completion of cytokinesis |
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TEKT2-dependent organization of the central spindle during anaphase is essential for proper midbody formation and the segregation of daughter cells after cytokinesis |
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involved in the stability and structural complexity of axonemal microtubules |
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may function as an outer dense fibers-affiliated molecule required for flagellum stability and sperm motility |