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FLASH GENE
Symbol TCF21 contributors: mct - updated : 29-05-2018
HGNC name transcription factor 21
HGNC id 11632
Location 6q23-q24      Physical location : 134.210.258 - 134.216.675
Synonym name pericardin,capsulin,podocyte expressed 1
Synonym symbol(s) POD1
DNA
TYPE functioning gene
STRUCTURE 3.00 kb     2 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned   linked   status provisional
Physical map
VNN1 6q23-q24 vanin 1 VNN3 6q23-q24 vanin 3 VNN2 6q23-q24 vanin 2 C6orf192 6q22.3-q23.3 chromosome 6 open reading frame 192 RPS12 6q23.1 ribosomal protein S12 LOC134870 6q23.1 similar to 60S ribosomal protein L23a EYA4 6q23 eyes absent homolog 4 (Drosophila) MGC34034 6q23.2 hypothetical protein MGC34034 TCF21 6q23-q24 transcription factor 21 FLJ35700 6q23.2 hypothetical protein FLJ35700 TBPL1 6q22.1-q22.3 TBP-like 1 SLC2A12 6q23.2 solute carrier family 2 (facilitated glucose transporter), member 12 SGK 6q23 serum/glucocorticoid regulated kinase LOC391971 6 similar to keratin 8; cytokeratin 8; keratin, type II cytoskeletal 8 LOC391972 6 similar to chromosome 7 open reading frame 17 protein; 16.7kD protein FAM8A6P 6q23 family with sequence similarity 8, member A6 pseudogene LOC154094 6q23.2 similar to Protein CGI-27 (C21orf19-like protein) ALDH8A1 6q24.1-q25.1 aldehyde dehydrogenase 8 family, member A1
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
Cardiovascularheart    
Reproductivemale systemtestis   
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
Membrane    
Membraneserouspericardiium  
Muscularstriatumcardiac  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal, pregnancy
Text mesenchymal and glomerular epithelial cells in the developing kidney,placenta,mesoderm
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
basic helix-loop-helix (HLH) motif protein
mono polymer heteromer , dimer
HOMOLOGY
interspecies homolog to murine Pod-1
Homologene
FAMILY basic helix-loop-helix family
CATEGORY transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus,chromatin/chromosome
CELLULAR PROCESS nucleotide, transcription
PHYSIOLOGICAL PROCESS development
text embryonic development,mesoderm development
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA binding to E-box (5'-CANNTG-3')
RNA
small molecule
protein e12 and e47
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS