Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TCF12 | contributors: mct/shn - updated : 11-10-2022 |
HGNC name | transcription factor 12 |
HGNC id | 11623 |
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Corresponding disease |
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Location | 15q21.3 Physical location : 57.210.832 - 57.580.712 | ||||
Synonym name | |||||
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Synonym symbol(s) | HTF4, HEB, HsT17266, bHLHb20, TCF-12, CRS3, HH26, HTF4, p64 |
DNA |
TYPE | functioning gene |
STRUCTURE | 373.22 kb 21 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
Map | cen - D15S121 - D15S962 - TCF12 - D15S998 - D15S1022 - qter |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Rna function | skeletal muscle, thymus and B cell |
Type |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage | HeLa, HPS-ALL T |
cell lines
fluid/secretion
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at STAGE |
physiological period | fetal |
Text | eye |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
interspecies | ortholog to Tcf12, Mus musculus |
ortholog to Tcf12, Rattus norvegicus | |
ortholog to tcf12, Danio rerio | |
ortholog to TCF12, Pan troglodytes |
intraspecies | paralog to TCF3, TCF4 |
Homologene |
FAMILY | |
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CATEGORY | transcription factor |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm | |
intracellular,nucleus,nucleoplasm,nuclear bodies,nuclear speckles | |
intracellular,nucleus,chromatin/chromosome |
basic FUNCTION | |
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CELLULAR PROCESS | nucleotide, transcription |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
Other | regulated by CBFA2T3-ZNF652 (CBFA2T3-ZNF652-mediated TCF12 regulation may play an important role in hematopoiesis and myogenesis) |
ASSOCIATED DISORDERS |
corresponding disease(s) | HH26 , CRS3 |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |