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FLASH GENE
Symbol TCEAL1 contributors: mct - updated : 04-01-2023
HGNC name transcription elongation factor A (SII)-like 1
HGNC id 11616
Location Xq22.2      Physical location : 102.883.647 - 102.885.874
Synonym symbol(s) SIIR, p21, pp21, WEX9
DNA
TYPE functioning gene
STRUCTURE 2.24 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 1200 21 159 - 1999 10051408
3 - 1188 21 159 - 1999 10051408
3 - 1215 21 159 - 1999 10051408
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Hearing/Equilibriumearinnercochlea highly
Nervousbrain   highly Homo sapiens
 brain   highly Homo sapiensFetal
 brainlimbic systemhippocampus highly Homo sapiens
 brainhindbraincerebellum highly Homo sapiens
 nervecranial nerve  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal   Homo sapiensAdult
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N-terminal domain helix-turn-helix (HTH) domain
  • p21/SIIR protein, Ser/Arg/Pro-rich nuclear phosphoprotein with arginine/serine (RS) domain
  • a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region
  • conjugated PhosphoP
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    intracellular,nucleus,nucleoplasm
    basic FUNCTION
  • transcription elongation factor A-like 1, modulating transcription in a promoter context-dependent fashion
  • potential role of TCEAL1 in the human nervous system
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS