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FLASH GENE
Symbol TCEA2 contributors: - updated : 05-06-2006
HGNC name transcription elongation factor A (SII), 2
HGNC id 11614
Location 20q13.33      Physical location : 62.688.438 - 62.703.699
Synonym symbol(s) S2T1, RP11-299N6.2, TFIIS
DNA
TYPE pseudogene
STRUCTURE 9.00 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1749 - 299 - Rual
- - 1661 - 272 - Rual
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Hearing/Equilibriumear   highly
Reproductivefemale systemuteruscervix highly
 female systemovary  highly
 male systemtestis  specific
Visualeye   highly
cells
SystemCellPubmedSpeciesStageRna symbol
Reproductivegerm cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a TFIIS-type zinc finger domain
HOMOLOGY
Homologene
FAMILY TFS-II family
CATEGORY RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
intracellular,nucleus
basic FUNCTION
  • transcription elongation factor A, RNA polymerase II, SII class
  • playing a necessary role for efficient RNA polymerase II transcription elongation past template-encoded arresting
  • sites
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacting with GRIPAP1 (regulation of GRIPAP1, testis-specific transcriptional activator)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS