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FLASH GENE
Symbol TBX10 contributors: npt - updated : 16-12-2002
HGNC name T-box 10
HGNC id 11593
Location 11q13      Physical location : 67.398.774 - 67.407.031
Synonym name
  • T-box 7
  • T-box transcription factor TBX10
    • Synonym symbol(s) TBX7, TBX13
    DNA
    TYPE functioning gene
    STRUCTURE 8.00 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map cen - TBX10 - D11S4087 - D11S916 - D11S4081 - qter
    Authors Law (98)
    Physical map
    ADRBK1 11q13.3 adrenergic, beta, receptor kinase 1 LOC338692 11q13.1 hypothetical protein LOC338692 SSH-3 11q13.1 slingshot 3 POLD4 11q13 polymerase (DNA-directed), delta 4 CLC 19q13.1 Charot-Leyden crystal protein RAD9A 11q13.1-q13.2 RAD9 homolog (S. pombe) PPP1CA 11q13.3 protein phosphatase 1, catalytic subunit, alpha isoform RPS6KB2 11q13.3 ribosomal protein S6 kinase, 70kDa, polypeptide 2 FLJ00332 11q13.1 FLJ00332 protein KIAA1394 11q13.1 KIAA1394 protein PTPRCAP 11q13 protein tyrosine phosphatase, receptor type, C-associated protein CORO1B 11q12.2 coronin, actin-binding protein, 1B LOC390212 11 similar to putative G-protein coupled receptor CABP4 11q13.1-q13.4 calcium binding protein 4 FLJ21749 11q13.1 hypothetical protein FLJ21749 AIP 11q13.3 aryl hydrocarbon receptor interacting protein PITPNM1 11q13 phosphatidylinositol transfer protein, membrane-associated 1 DOC-1R 11q13 tumor suppressor deleted in oral cancer-related 1 CABP2 11q13.1 calcium binding protein 2 GSTP1 11q13.3 glutathione S-transferase pi FLJ90834 11q13.1 hypothetical protein FLJ90834 NDUFV1 11q13 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa LOC390213 11 similar to Double C2, gamma NUDT8 11q13.1 nudix (nucleoside diphosphate linked moiety X)-type motif 8 TBX10 11q13 T-box 10 ACY-3 11q13.1 aspartoacylase-3 ALDH3B2 11q13 aldehyde dehydrogenase 3 family, member B2 RPL37P2 11q13 ribosomal protein L37 pseudogene 2 LOC132740 11q13.1 similar to unc-93 homolog B1; unc93 (C.elegans) homolog B; unc-93 related protein LOC390215 11 similar to seven transmembrane helix receptor OR7E11P 11q11 olfactory receptor, family 7, subfamily E, member 11 pseudogene LOC390216 11 similar to mannosyltransferase LOC158490 11q13.1 similar to hypothetical protein FLJ10661 LOC387785 11 LOC387785
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 1557 42 385 - Bush (2003)
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestine    
    Lymphoid/Immunelymph node    
    Reproductivefemale systemuterus   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period embryo, fetal, pregnancy
    Text kidney
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a large N terminal DNA binding domain (T-box)
    • HOMOLOGY
    interspecies homolog to murine T-box gene Tbx1 (T,brachyury)
    Homologene
    FAMILY
  • T-box family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • involved in the regulation of developmental processes
  • exhibits a unique spatio-temporal pattern during hindbrain development
    • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS development
    text regulation
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding through T-box
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS