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FLASH GENE
Symbol TBC1D5 contributors: mct - updated : 05-01-2011
HGNC name TBC1 domain family, member 5
HGNC id 19166
Location 3p24.3      Physical location : 17.198.654 - 17.784.240
Synonym symbol(s) KIAA0210, TBC5
DNA
TYPE functioning gene
STRUCTURE 585.59 kb     24 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
22 - 6631 - 795 - 1996 9039502
isoform b
24 - 6534 - 817 - 1996 9039502
isoform a
22 - 7869 - 795 - 1996 9039502
isoform b
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen   highly
Cardiovascularheart   highly
Nervousbrain    
 gangliasensory gangliadorsal root  
 spinal cord    
Reproductivefemale systemovary   
 female systemuterus   
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
Nervouscentral   
Nervousperipherous   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • TBC domain
  • HOMOLOGY
    Homologene
    FAMILY
  • Rab GAP family of proteins
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    basic FUNCTION
  • putative GTPase activator protein of RAB-like small GTPase
  • retromer-interacting protein, negatively regulating VPS35/VPS29/VPS26A recruitment and causing RAB7A to dissociate from the membrane
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS