Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

TBC1D2

contributors: mct - updated : 05-01-2011

HGNC name	TBC1 domain family, member 2
HGNC id	18026

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	9q22.33      Physical location : 100.961.280 - 101.018.003
Synonym name	prostate antigen recognized and identified by SEREX 1
	armus
Synonym symbol(s)	PARIS1, PARIS-1, DKFZP761D1823, TBC1D2A, FLJ16244, FLJ42782, PP8997

DNA

TYPE	functioning gene
STRUCTURE	56.72 kb     13 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_018421 13 - 3330 NP_060891 - 917 - 2002 11785977

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain         Reproductive male system prostate       Respiratory lung           respiratory tract larynx

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial

cell lineage
cell lines	prostate carcinoma cell lines
fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	one RAB-GAP TBC domain
	one PH domain

HOMOLOGY

Homologene

FAMILY

Rab-GAP family

CATEGORY

regulatory , transport

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytosolic,vesicle
	intracellular,nucleus

basic FUNCTION	acting as a GTPase activating protein for Rab family proteins
	may play a role in regulation of cell differentiation and growth

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

cellular trafficking transport

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

RAB-like small GTPases

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS