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FLASH GENE
Symbol TAS2R46 contributors: npt - updated : 26-02-2004
HGNC name taste receptor, type 2, member 46
HGNC id 18877
Location 12p13.31      Physical location : 11.213.963 - 11.214.893
Synonym name bitter taste receptor
Synonym symbol(s) T2R54, TAS2R54, MGC134865
DNA
TYPE functioning gene
STRUCTURE 0.00 kb     1 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
DKFZp761P1010 12p13.31 hypothetical protein DKFZp761P1010 CSDA 12p13.1 cold shock domain protein A LOC387838 12 LOC387838 TAS2R7 12p13 taste receptor, type 2, member 7 TAS2R8 12p13 taste receptor, type 2, member 8 TAS2R9 12p13 taste receptor, type 2, member 9 TAS2R10 12p13 taste receptor, type 2, member 10 PROL4 12p13 proline rich 4 (lacrimal) PRH1 12p13.2 proline-rich protein HaeIII subfamily 1 PRH2 12p13.2 proline-rich protein HaeIII subfamily 2 TAS2R13 12p13 taste receptor, type 2, member 13 TAS2R14 12p13 taste receptor, type 2, member 14 PS8 12p13.31 bitter taste receptor pseudogene 8 TAS2R50 12p13.31 taste receptor, type 2, member 50 TAS2R49 12p13.31 taste receptor, type 2, member 49 TAS2R48 12p13.31 taste receptor, type 2, member 48 TAS2R44 12p13.31 taste receptor, type 2, member 44 TAS2R63P 12p13.31 taste receptor, type 2, member 63 pseudogene TAS2R46 12p13.31 taste receptor, type 2, member 46 TAS2R64P 12p13.31 taste receptor, type 2, member 64 pseudogene TAS2R43 12p13.31 taste receptor, type 2, member 43 hT2R55 12p13 candidate taste receptor hT2R55 PRB3 12p13.2 proline-rich protein BstNI subfamily 3 PRB4 12p13.2 proline-rich protein BstNI subfamily 4 PRB1 12p13.2 proline-rich protein BstNI subfamily 1 LOC341461 12p13.31 similar to hypothetical protein LOC390295 12 similar to KIAA1595 protein
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
1 - 930 35 309 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
digestivemouthpalate   
Digestivemouthtongue   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsensorygustatory  
cells
SystemCellPubmedSpeciesStageRna symbol
Gustatoryclear receptor cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven transmembrane segments (7TM) receptor
  • an extracellular lignand binding domain
  • HOMOLOGY
    Homologene
    FAMILY
  • G protein coupled receptor superfamily
  • taste receptor family
  • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION involved in bitter perception
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction , sensory transduction/taste
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS