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FLASH GENE
Symbol TAS2R43 contributors: mct/npt - updated : 16-05-2009
HGNC name taste receptor, type 2, member 43
HGNC id 18875
Location 12p13.2      Physical location : 11.243.885 - 11.244.912
Synonym symbol(s) T2R52
DNA
TYPE functioning gene
STRUCTURE 1.03 kb     1 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
1 - 1027 35.5 309 - Sainz (2007)
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
digestivemouthpalate   
Digestivemouthtongue   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsensorygustatory  
cells
SystemCellPubmedSpeciesStageRna symbol
Gustatoryclear receptor cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven transmembrane segments (7TM) receptor
  • an extracellular lignand binding domain
  • HOMOLOGY
    Homologene
    FAMILY
  • G protein coupled receptor superfamily
  • taste receptor (T2R) family
  • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in bitter perception
  • receptor for denatonium (Sainz 2007)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction , sensory transduction/taste
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS