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FLASH GENE
Symbol TAS2R4 contributors: mct - updated : 10-10-2011
HGNC name taste receptor, type 2, member 4
HGNC id 14911
Location 7q34      Physical location : 141.478.288 - 141.479.188
Synonym name candidate taste receptor T2R4
Synonym symbol(s) T2R4, MGC163311
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 0.00 kb     1 Exon(s)
10 Kb 5' upstream gene genomic sequence study
motif Viral sequence   gene pol
repetitive sequence
text structure SNP (involving bitter tasting)
MAPPING cloned Y linked N status provisional
Map cen - TAS2R16 - TAS2R3 - TAS2R4 - TAS2R5 - qter
Authors Adler (00)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
1 - 900 - 299 - Hillier (2003)
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouthtongue   
digestivemouthpalate   
Nervousbrainforebraincerebral cortex   Homo sapiens
 brainhindbraincerebellum   Homo sapiens
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsensorygustatory  
Muscularsmoothmuscularis mucosa (tractus digestif)   Homo sapiens
cells
SystemCellPubmedSpeciesStageRna symbol
Digestiveepithelial cell Homo sapiens
Gustatoryclear receptor cell
Respiratoryepithelial cell Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven transmembrane segments (7TM) receptor
  • an extracellular lignand binding domain
  • HOMOLOGY
    Homologene
    FAMILY
  • G protein coupled receptor superfamily
  • taste receptor family
  • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in bitter perception
  • utilized to recognize and perceive the structure and bitterness of peptides
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction , sensory transduction/taste
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by bitter peptides
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS