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FLASH GENE
Symbol TARP contributors: mct/npt - updated : 29-10-2009
Location 7p14.1      Physical location : 38.299.243 - 38.313.248
Genatlas name TCR gamma alternate reading frame protein
Synonym name
  • T cell receptor gamma chain
  • T-cell receptor gamma-chain constant region
  • Synonym symbol(s) TCRGC1, CD3G, TCRG, TCRGC2
    DNA
    TYPE functioning gene
    STRUCTURE 14.00 kb     4 Exon(s)
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 1027 7 58 - Wolfgang (2000)
  • using the upstream ORF
  • localized to the outer mitochondrial membrane
  • including 5 leucines in heptad repeats followed by a basic region
  • 4 exons
  • 4 - 1027 12 111 - Wolfgang (2000)
  • using the downstream ORF
  • similar to but shorter than TRG@ proteins
  • 4 exons
  • EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunespleen   highly
     thymus   moderately
    Nervousnerve   highly
    Reproductivemale systemprostate  predominantly
    cell lineage
    cell lines
    fluid/secretion blood
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • may playing a role in regulating growth and gene expression in prostate cancer cells
  • play an important role in anti-tumor/microbe immune responses
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by testosterone
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS