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FLASH GENE
Symbol TAL2 contributors: mct - updated : 02-12-2009
HGNC name T-cell acute lymphocytic leukemia 2
HGNC id 11557
Location 9q31.2      Physical location : 108.424.737 - 108.425.383
Synonym symbol(s) bHLHa19
DNA
TYPE functioning gene
STRUCTURE 0.33 kb     1 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Physical map
LOC138802 9q31.3 similar to Olfactory receptor 13C8 LOC392375 9 similar to olfactory receptor LOC138799 9q31.3 similar to Olfactory receptor 13C5 LOC392376 9 similar to Olfactory receptor 13C2 LOC286362 9q31.3 similar to Olfactory receptor 13C9 LOC392377 9 similar to olfactory receptor LOC286365 9q31.3 similar to seven transmembrane helix receptor LOC392378 9 similar to Olfactory receptor 13D1 NIPSNAP3A 9q31.3 nipsnap homolog 3A (C. elegans) NIPSNAP3B 9q31.3 nipsnap homolog 3B (C. elegans) ABCA1 9q31.1 ATP-binding cassette, sub-family A (ABC1), member 1 CTL1 CSDUFD1 9q31 cystatin and DUF19 domain containing 1 LOC389779 9 similar to fibronectin type 3 and SPRY (spla, ryanodine) domain containing (with coiled-coil motif) 1; fibronectin type 3 and SPRY domain-containing protein LOC389780 9 similar to KIAA0884 protein LOC389781 9 similar to tuberin-like protein 1; tulip 1 protein; GAP-related interacting partner to E12 GARNL2 9q31 GTPase activating RANGAP domain-like 2 FCMD 9q31 Fukuyama type congenital muscular dystrophy (fukutin) TAL2 9q31.2 T-cell acute lymphocytic leukemia 2 FLJ10493 9q31.3 hypothetical protein FLJ10493 LOC392379 9 similar to constitutive photomorphogenic protein
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
1 - 656 - 108 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/ImmuneT cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • basic helix-loop-helix (HLH) protein
  • HOMOLOGY
    interspecies homolog to TAL1
    Homologene
    FAMILY
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in T cell acute lymphoblastic leukemia
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   translocation --over  
    T-cell acute lymphoblastic leukemia with t(7;9)(q35;q34)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS