Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TAF4B | contributors: mct - updated : 21-05-2016 |
HGNC name | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
HGNC id | 11538 |
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Corresponding disease |
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Location | 18q11.2 Physical location : 23.806.408 - 23.971.647 | ||
Synonym name | |||
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Synonym symbol(s) | TAF2C2, TAFII105, TAFII105ALPHA |
DNA |
TYPE | functioning gene |
STRUCTURE | 165.38 kb 15 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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text structure |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
intraspecies | homolog to related to TAFII 130 |
Homologene |
FAMILY |
CATEGORY | enzyme , transcription factor |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm | |
intracellular,nucleus,nucleoplasm | |
intracellular,nucleus,chromatin/chromosome | |
intracellular,nucleus,nucleolus |
basic FUNCTION | |
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CELLULAR PROCESS | nucleotide, transcription |
PHYSIOLOGICAL PROCESS | development |
text | ovarian development |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA | binding to a subset of NF-kappa B gene |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
induced by | MYC, that directly induces TAF4B expression, through one of the non-canonical E-box sites, which is in a highly conserved region of TAF4B promoters |
ASSOCIATED DISORDERS |
corresponding disease(s) | SPGF13 |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |
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