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FLASH GENE

Symbol

TAAR2

contributors: mct/npt - updated : 06-02-2009

HGNC name	trace amine associated receptor 2
HGNC id	4514

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	6q23.2      Physical location : 132.938.288 - 132.945.414
Synonym name	G protein-coupled receptor 58
Synonym symbol(s)	GPR58, GPR57, TAAR3

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster
text	TAAR cluster
STRUCTURE	7.13 kb     2 Exon(s)

motif

repetitive sequence   ALU   long interspersed repetitive elements

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 2 - 1056 40 351 - Lindemann (2005) variant 2 - - 944 35 306 - Lindemann (2005)

EXPRESSION

Type	restricted

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain hindbrain cerebellum       brain diencephalon hypothalamus

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	seven predicted transmembrane domain
	Pkc phosphorylation site

HOMOLOGY

intraspecies	homolog to PNR
	homolog to HTR4
	homolog to GPR57

Homologene

FAMILY

G-protein coupled receptor 1 family

CATEGORY

receptor membrane G

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular,cytoplasm,organelle,lysosome

basic FUNCTION	may have a function associated with the detection of social cues (Liberles 2006)
	endogenous compounds structurally related to classical biogenic amines (Lindemann 2005)

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

signal transduction

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS