SUBCELLULAR LOCALIZATION
| intracellular
|
| intracellular,cytoplasm,organelle,mitochondria,inner
|
| intracellular,cytoplasm,organelle,mitochondria,matrix
|
| intracellular,cytoplasm,organelle,membrane
|
text
| present in the mitochondrial matrix ![](pubmed.jpg) |
basic FUNCTION
| manganese superoxide dismutase catabolic pathway of activated oxygen species, free radical detoxification |
|
destroying radical which are normally produced within the cells and which are toxic to biological system |
|
acting as an iron toxicity modifier |
|
function as the first line of antioxidant defense against highly reactive superoxide radicals |
|
with MIF appear to be early predictors for survival in septic patients ![](pubmed.jpg) |
|
binds with ubiquitin molecules to form polyubiquitination chains and undergoes degradation through the ubiquitin-proteasomal pathway ![](pubmed.jpg) |
|
major mitochondrial antioxidative enzyme, constituting an important control switch in the process of activation-induced oxidative signal generation in T cells ![](pubmed.jpg) |
|
critical role for SOD2 and mitochondria in the regulation of human T cell activation ![](pubmed.jpg) |
|
regulates a "metabolic switch" during progression from quiescent through the proliferative cycle ![](pubmed.jpg) |
|
is potentially a new molecular player contributing to the Warburg effect ![](pubmed.jpg) |