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FLASH GENE
Symbol SYTL5 contributors: mct - updated : 22-04-2011
HGNC name synaptotagmin-like 5
HGNC id 15589
Location Xp21.1      Physical location : 37.865.834 - 37.988.072
Synonym symbol(s) SLP5
DNA
TYPE functioning gene
STRUCTURE 92.00 kb     16 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
an intravesicular N terminal domain made of two conserved regions SHD1 and SHB2 fonctioning as protein interaction sites,a single transmembrane (TM) region,two protein kinase C-homologous repeats (Ca2+ binding domains C2) and a conserved WHXL motif in the C terminus
HOMOLOGY
Homologene
FAMILY
  • C type tandem C2 protein family (SLP family)
  • synaptotagmin family
  • CATEGORY regulatory , transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,vesicle
    basic FUNCTION
  • involved in RAB27A dependent membrane trafficking in specific tissues
  • with SYT7, are positive regulators of chemotaxis (
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text vesicular trafficking
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein RAB27A (GTP bound form) binding
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS