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FLASH GENE

Symbol

SYT9

contributors: np/ - updated : 16-03-2004

HGNC name	synaptotagmin IX
HGNC id	19265

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	11p15.4      Physical location : 7.273.180 - 7.490.276
Synonym name	synaptotagmin 9
Synonym symbol(s)	FLJ45896, SytIX

DNA

TYPE	functioning gene
STRUCTURE	217.10 kb     7 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_175733 7 - 3958 NP_783860 56.05 491 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain       specific

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	an intravesicular N terminal domain
	a single transmembrane (TM) region at the N-terminus
	two protein kinase C-homologous repeats (Ca2+ binding domains C2), C2A and C2B and a conserved WHXL motif in the C terminus

mono polymer

homomer , heteromer , complex

HOMOLOGY

interspecies

ortholog to murine Syt5

intraspecies

homolog to SYT1

Homologene

FAMILY

synaptotagmin family

CATEGORY

structural protein

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular
	intracellular,cytoplasm,cytosolic,vesicle
text	synaptis vesicles

basic FUNCTION	may be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain
	having a modulatory calcium dependent function

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	metal binding,
	Ca2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS